Assistant Professor of Chemical Engineering

Research Areas

Biochemical Sensor

Research Interests

Sensor Technology for Future Biopharmaceuticals
As the definition of pharmaceutics broadens to include engineered living cells and their molecular products, there is a significant scientific need for fundamentally new approaches to understand this new type of ‘drugs’. However, this necessarily requires a new generation of non-destructive and label-free techniques that can characterize a single cell and their molecular product at high-throughput.
Under this new paradigm, our team are interested in development of non-destructive and high-throughput analytic tools of living cell and biomolecules using a new nanosensor technology and advanced hardware system. For this, we explore the scientific question that what optical, material, and instrumental interfaces can be combined to bring these powerful sensor tools to high-throughput monitoring form factors of biopharmaceutical products. Our ultimate goal is to combine the advanced sensor hardware into continuous biopharmaceutical line for the online monitoring.

Selected Publications

1. Cho et al., “Antibody-Free Rapid Detection of SARS-CoV-2 Proteins Using Corona Phase Molecular Recognition to Accelerate Development Time” Analytical Chemistry 2021, 93, 14685-14693
2. Cho et al., “Nanosensor Chemical Cytometry for Characterizing the Efflux Heterogeneity of Nitric Oxide from Macrophages” ACS Nano 2021, 15, 13683-13691
3. Cho et al., “Cellular Lensing and Near Infrared Fluorescent Nanosensor Arrays to Enable Chemical Efflux Cytometry”, Nature Communications 2021, 12, 3079
4. Cho et al., “A Fiber Optic Interface Coupled to Nanosensors: Applications to Protein Aggregation and Organic Molecule Quantification” ACS Nano 2020, 14, 10141-10152
5. Cho et al., “Multi-Array Nanopattern Electronic-Nose (E-Nose) by High-Resolution Top-Down Nanolithography” Advanced Functional Materials 2020, 30, 2002486
6. Cho et al., “Continuous Meter-scale Synthesis of Weavable Tunicate Cellulose/Carbon Nanotube Fibers for High-Performance Wearable Sensors”, ACS Nano 2019, 138, 9332-9341
7. Cho et al., “Ultra-sensitive VOCs Detection of High-Resolution CuO/Cu2O/Ag Nanopattern Sensor”, Advanced Functional Materials 2019, 29, 1808319
8. Cho et al., “Polyelemental Nanopattern via Plasma Ion Bombardment: From Fabrication to Superior H2 Sensing Application”, Advanced Materials 2019, 31, 1805343
9. Cho et al., “Superior Chemical Sensing Performance of Black Phosphorus: Comparison with MoS2 and Graphene” Advanced Materials 2016, 28, 7020-7028
10. Cho et al., “High-Resolution p-type Metal Oxide Nanowire Array for Ultrasensitive Volatile Organic Compounds Sensor”, Nano Letters 2016, 16, 4508-4515
11. Cho et al., “Highly Enhanced Gas Adsorption Properties in Vertically Aligned MoS2 Layers”, ACS Nano 2015, 9, 9314-9321

Professional Experience

2019 – 2022 Massachusetts Institute of Technology 박사후연구원
2016 – 2016 University of California, Berkeley 방문연구원