Professor of Chemical Engineering

Research Areas

Advanced Bio-inspired Materials and Immunoengineering

Research Interests

THE UM LABORATORY COMPREHENSIVELY BLENDS NANOTECHNOLOGY & BIOMEDICAL ENGINEERING CONCEPTS & PRINCIPLES
Specially, we have much research interest in replicating Mother Nature system for smart and advanced nanotechnology and further assessing it for several biomedical issues where cell-environment interactions are critical. The novel Nature-inspired (or bio-inspired) materials modulate the cellular function by mimicking some programmable signals derived from Nature system; they’re also used to create in vitro and in vivo microenvironment model under which we might understand critical biology questions and study several medical challenges. To meet this goal, we may need an interdisciplinary cooperation, in which the art chemistry, polymer science, physics, mathematics, and immunology are tightly combined to each other.

DESIGN OF NOVEL NANOSTRUCTURED MATERIALS VIA POLYMERIC ENGINEERING TOOL KITS
It may include versatile nanostructured materials. Synthetic particles with multifunctional compartments may prove a series of interesting biological issues such as specific-selective anisotropy and hierarchical self-assembly among biomolecules. In addition, we establish program software for the rational design of such engineered polymeric nanostructures.

CELLULAR IMMUNOENGINEERING FOR TARGETED INFECTED DISEASES
Rationally designed and polymeric nanostructures are incorporated with medicinal cell types (containing lymphocytes or stem cells) and may be utilized to effectively tune cellular functions or metabolism for therapeutic purpose. Outstanding medical therapy may be achieved together with remote controllable nanostructured materials carrying with a variety of immune-signal modules (e.g., cytokines or chemokines), to heal several infected diseases including cancer or HIV

Selected Publications

1.Moon, J. J., Um, S. H. et. al. Nature Materials (Accepted) (2011)

2.Stephane, M. Moon, J. J. UM, S. H. Irvine, D.J. Nature Medicine (Accepted) (2010)

3.Um, S. H. et al. Nature Protocols, 4(12), 1759-1770 (2009)

4.Um, S. H. et al. Nature Materials, 8(5), 432-437(2009)

5.Lee, JB. Noh, YH. Um, S. H. Luo, D. Nature Nanotechnology, 4(7), 430-436 (2009)

6.Um, S. H. et. al. Nature Protocols, 1(2), 995-1000 (2006)

7.UM, S. H. et al, Nature Materials, 5(10), 797-801 (2006)

Professional Experience

조교수 (광주과학기술원, 2009-2011)
연구원(Howard Huges Medical Institute, 2009)
박사후 연구원 (Massachusetts Institute of Technology, 2007-2009)